20+
Core invention patents
Business Unit
Qidaohui Institute
Integrated solutions for hazardous-reaction continuous processing, covering process development, equipment engineering, automation control, and industrial implementation.
Company Overview
Qidaohui focuses on continuous-flow microchemical technology for high-risk reaction systems, serving fine chemicals, pharmaceuticals, agrochemicals, and advanced materials sectors.
2000m²+
Manufacturing and testing space
20+
Industrial application projects
Gram to kt/a
Scale-up delivery experience
Core Capabilities
Process Development
- Pretreatment + reaction + post-treatment full workflow
- Nitration, hydrogenation, oxidation, esterification, chlorination, hydrolysis
- Package transfer and pilot-to-industrial support
Equipment Engineering
- Microreactors, extraction units, jet reactors, evaporation systems
- Modular design with staged mixing and staged temperature control
- Custom non-standard integrated skids
Automation and Safety
- DCS-based online monitoring and control
- SIS strategy for critical hazardous processes
- Emergency shutdown and interlock design
Product and Equipment
Continuous-Flow Microreactors
- High precision structure for fast heat/mass transfer
- Flexible serial/parallel scale-up
- Suitable for highly exothermic and hazardous reactions
Continuous Extraction Units
- High separation efficiency and compact footprint
- Continuous liquid-liquid extraction scenarios
- Lower manual intervention
Jet Reactors
- Venturi-driven fast mixing and mass transfer
- Improved selectivity window for fast reactions
- Suitable for multiphase systems
Evaporation Systems
- Combined evaporation routes for efficiency improvement
- Custom design for special process constraints
- Balanced purity, energy, and stability
Process Package Service
Cooperation Models
- Package transfer with startup guidance
- Package + engineering design
- Package + EPC delivery
Scope
- Nitration, fluorination, hydrogenation, esterification, chlorination, oxidation, hydrolysis
- Continuous and safer route for fine chemical production
- Integrated separation and automation support
Cases and Comparison
| Scenario | Batch Route | Continuous Route |
|---|---|---|
| Isooctyl Nitrate | Cycle 5~10h with multiple batch operations | 15~240s reaction window with continuous operation |
| 2-Nitromesitylene | Low-temp dropwise route with long manual sequence | Pumped feed + micro-mixing + rapid phase separation |
| Safety Control | Higher local hotspot and runaway risk | Real-time temp/pressure supervision with interlocks |
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